Critical Role of Neuronal Vps35 in Blood Vessel Branching and Maturation in Developing Mouse Brain

Vps35 (vacuolar protein sorting 35), a key component of retromer, plays a crucial role in selective retrieval of transmembrane proteins from endosomes to trans-Golgi networks. Dysfunctional Vps35/retromer is a risk factor for the development of neurodegenerative diseases. Vps35 is highly expressed i...

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Bibliographic Details
Main Authors: Yang Zhao, Daehoon Lee, Xiao-Juan Zhu, Wen-Cheng Xiong
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/7/1653