Tomo-seq identifies NINJ1 as a potential target for anti-inflammatory strategy in thoracic aortic dissection

Tomo-seq identifies NINJ1 as a potential target for anti-inflammatory strategy in thoracic aortic dissection

Abstract Background Thoracic aortic dissection (TAD) is a life-threatening disease caused by an intimal tear in the aorta. The histological characteristics differ significantly between the tear area (TA) and the distant area. Previous studies have emphasized that certain specific genes tend to clust...

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Bibliographic Details
Main Authors: Yixuan Sheng, Liying Wu, Yuan Chang, Wendao Liu, Menghao Tao, Xiao Chen, Xiong Zhang, Bin Li, Ningning Zhang, Dongting Ye, Chunxi Zhang, Daliang Zhu, Haisen Zhao, Aijun Chen, Haisheng Chen, Jiangping Song
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Medicine
Subjects:
Thoracic aortic dissection
Aortic remodeling
Tomo-seq
Immune
NINJ1
Inflammation
Online Access:https://doi.org/10.1186/s12916-023-03077-1

Internet

https://doi.org/10.1186/s12916-023-03077-1

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