A Porous Reservoir-Backed Boronate Gel Microneedle for Efficient Skin Penetration and Sustained Glucose-Responsive Insulin Delivery

A Porous Reservoir-Backed Boronate Gel Microneedle for Efficient Skin Penetration and Sustained Glucose-Responsive Insulin Delivery

Recently, phenylboronic acid (PBA) gel containing microneedle (MN) technology with acute and sustained glucose-sensitive functionality has attracted significant research attention. Herein, we report a polyvinyl alcohol(PVA)-coated MNs patch with an interconnected porous gel drug reservoir for enhanc...

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Bibliographic Details
Main Authors: Siyuan Chen, Takuya Miyazaki, Michiko Itoh, Hiroko Matsumoto, Yuki Moro-oka, Miyako Tanaka, Yuji Miyahara, Takayoshi Suganami, Akira Matsumoto
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Gels
Subjects:
phenylboronic acid
gel
glucose-responsive
microneedle
insulin
drug reservoir
Online Access:https://www.mdpi.com/2310-2861/8/2/74

Internet

https://www.mdpi.com/2310-2861/8/2/74

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