Molecular Interactions of the Copper Chaperone Atx1 of <i>Paracoccidioides brasiliensis</i> with Fungal Proteins Suggest a Crosstalk between Iron and Copper Homeostasis

Molecular Interactions of the Copper Chaperone Atx1 of <i>Paracoccidioides brasiliensis</i> with Fungal Proteins Suggest a Crosstalk between Iron and Copper Homeostasis

<i>Paracoccidioides</i> spp. are endemic fungi from Latin America that cause Paracoccidioidomycosis, a systemic disease. These fungi present systems for high-affinity metal uptake, storage, and mobilization, which counteract host nutritional immunity and mitigate the toxic effects of met...

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Bibliographic Details
Main Authors: Marcos Antonio Batista de Carvalho Júnior, Lana O’Hara Souza Silva, Laurine Lacerda Pigosso, Aparecido Ferreira de Souza, Danize Eukales Menezes Lugo, Dayane Moraes, Kleber Santiago Freitas e Silva, Maristela Pereira, Célia Maria de Almeida Soares
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Microorganisms
Subjects:
<i>Paracoccidioides brasiliensis</i>
Atx1
protein–protein interaction
pull-down
mass spectrometry
Cyb5
Online Access:https://www.mdpi.com/2076-2607/11/2/248

Internet

https://www.mdpi.com/2076-2607/11/2/248

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