Exploiting Botulinum Neurotoxins for the Study of Brain Physiology and Pathology
Botulinum neurotoxins are metalloproteases that specifically cleave N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins in synaptic terminals, resulting in a potent inhibition of vesicle fusion and transmitter release. The family comprises different serotypes (BoNT/A to Bo...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-04-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/10/5/175 |