PVP/aprepitant microcapsules produced by supercritical antisolvent process

Abstract The supercritical antisolvent (SAS) process was a green alternative to improve the low bioavailability of insoluble drugs. However, it is difficult for SAS process to industrialize with limited production capacity. A coaxial annular nozzle was used to prepare the microcapsules of aprepitant...

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Bibliographic Details
Main Authors: Zhuo Zhang, Guizhou Hao, Xuemei Sun, Feibo Wang, Dengbo Zhang, Dedong Hu
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-60323-z