IGFBP3 inhibits tumor growth and invasion of lung cancer cells and is associated with improved survival in lung cancer patients

The insulin-like growth factor (IGF)-pathway is involved in tumor cell proliferation, metastasis, and survival. We aimed to find out what effects IGF binding protein 3 (IGFBP3) exerted on H1299 lung cancer (LC) cells in terms of tumor growth and invasion and whether IGFBP3 was associated with clinic...

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Bibliographic Details
Main Authors: Hartmut Kuhn, Armin Frille, Marie Anna Petersen, Jonas Oberhuber-Kurth, Lukas Hofmann, Albrecht Gläser, Sabine Taubenheim, Sabine Klagges, Sebastian Kraemer, Johannes Broschewitz, Maximilian von Laffert, Hubert Wirtz
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332200225X