IGFBP3 inhibits tumor growth and invasion of lung cancer cells and is associated with improved survival in lung cancer patients

IGFBP3 inhibits tumor growth and invasion of lung cancer cells and is associated with improved survival in lung cancer patients

The insulin-like growth factor (IGF)-pathway is involved in tumor cell proliferation, metastasis, and survival. We aimed to find out what effects IGF binding protein 3 (IGFBP3) exerted on H1299 lung cancer (LC) cells in terms of tumor growth and invasion and whether IGFBP3 was associated with clinic...

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Bibliographic Details
Main Authors: Hartmut Kuhn, Armin Frille, Marie Anna Petersen, Jonas Oberhuber-Kurth, Lukas Hofmann, Albrecht Gläser, Sabine Taubenheim, Sabine Klagges, Sebastian Kraemer, Johannes Broschewitz, Maximilian von Laffert, Hubert Wirtz
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332200225X

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