ALKBH5‐mediated m6A demethylation ameliorates extracellular matrix deposition in cutaneous pathological fibrosis

ALKBH5‐mediated m6A demethylation ameliorates extracellular matrix deposition in cutaneous pathological fibrosis

Abstract Background Elevated extracellular matrix (ECM) accumulation is a major contributing factor to the pathogenesis of fibrotic diseases. Recent studies have indicated that N6‐methyladenosine (m6A) RNA modification plays a pivotal role in modulating RNA stability and contribute to the initiation...

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Bibliographic Details
Main Authors: Ruoqing Xu, En Yang, Hsin Liang, Shenying Luo, Yunhan Liu, Yimin Khoong, Haizhou Li, Xin Huang, Yixuan Zhao, Tao Zan
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Clinical and Translational Medicine
Subjects:
ALKBH5
ECM
hypertrophic scar
m6A modification
Online Access:https://doi.org/10.1002/ctm2.70016

Internet

https://doi.org/10.1002/ctm2.70016

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