A Self-Assembled G-Quadruplex/Hemin DNAzyme-Driven DNA Walker Strategy for Sensitive and Rapid Detection of Lead Ions Based on Rolling Circle Amplification

A Self-Assembled G-Quadruplex/Hemin DNAzyme-Driven DNA Walker Strategy for Sensitive and Rapid Detection of Lead Ions Based on Rolling Circle Amplification

Herein, a sensitive biosensor is constructed based on a novel rolling circle amplification (RCA) for colorimetric quantification of lead ion (Pb<sup>2+</sup>). At the detection system, GR5 DNAzymes are modified on the surface of an immunomagnetic bead, and Pb<sup>2+</sup> is...

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Bibliographic Details
Main Authors: Yuhan Wang, Jiaxuan Xiao, Xiaona Lin, Amira Waheed, Ayyanu Ravikumar, Zhen Zhang, Yanmin Zou, Chengshui Chen
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biosensors
Subjects:
biosensor
rapid detection
signal amplification
rolling circle amplification
G-quadruplex
Online Access:https://www.mdpi.com/2079-6374/13/8/761

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https://www.mdpi.com/2079-6374/13/8/761

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