Arcuate AgRP, but not POMC neurons, modulate paraventricular CRF synthesis and release in response to fasting

Abstract Background The activation of the hypothalamic–pituitary–adrenal (HPA) axis is essential for metabolic adaptation in response to fasting. However, the neurocircuitry connecting changes in the peripheral energy stores to the activity of hypothalamic paraventricular corticotrophin-releasing fa...

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Bibliographic Details
Main Authors: Alan Carlos Alves Fernandes, Franciane Pereira de Oliveira, Gimena Fernandez, Luane da Guia Vieira, Cristiane Gugelmin Rosa, Taís do Nascimento, Suzelei de Castro França, Jose Donato, Kristen R. Vella, Jose Antunes-Rodrigues, André Mecawi, Mario Perello, Lucila Leico Kagohara Elias, Rodrigo Rorato
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-022-00853-z