Organotypic endothelial adhesion molecules are key for Trypanosoma brucei tropism and virulence

Organotypic endothelial adhesion molecules are key for Trypanosoma brucei tropism and virulence

Summary: Trypanosoma brucei is responsible for lethal diseases in humans and cattle in Sub-Saharan Africa. These extracellular parasites extravasate from the blood circulation into several tissues. The importance of the vasculature in tissue tropism is poorly understood. Using intravital imaging and...

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Bibliographic Details
Main Authors: Mariana De Niz, Daniela Brás, Marie Ouarné, Mafalda Pedro, Ana M. Nascimento, Lenka Henao Misikova, Claudio A. Franco, Luisa M. Figueiredo
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
tropism
vasculature
parasites
Trypanosoma brucei
intravital microscopy
endothelial receptors
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721011943

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http://www.sciencedirect.com/science/article/pii/S2211124721011943

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