Inhibition of ABCB1 activity in cerebrovascular disease may increase pharmacotherapy effectiveness

Introduction. Despite the development of numerous drugs with neuroprotective activity, their efficacy in cerebrovascular disease remains low, which may partly be due to the efflux function of protein ABCB1 and insufficient penetration of the blood-brain barrier by these drugs. Aim to evaluate the...

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Bibliographic Details
Main Authors: Ivan V. Chernykh, Aleksey V. Shchulkin, Sergei K. Pravkin, Maria V. Gatsanoga, Elena N. Yakusheva
Format: Article
Language:English
Published: Research Center of Neurology 2021-03-01
Series:Анналы клинической и экспериментальной неврологии
Subjects:
Online Access:https://annaly-nevrologii.com/journal/pathID/article/viewFile/728/568