Expression levels of NONO, a nuclear protein primarily involved in paraspeckles function, are associated with several deregulated molecular pathways and poor clinical outcome in multiple myeloma

Expression levels of NONO, a nuclear protein primarily involved in paraspeckles function, are associated with several deregulated molecular pathways and poor clinical outcome in multiple myeloma

Abstract Purpose The NONO protein belongs to the multifunctional family of proteins that can bind DNA, RNA and proteins. It is located in the nucleus of most mammalian cells and can affect almost every step of gene regulation. Dysregulation of NONO has been found in many types of cancer; however, da...

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Bibliographic Details
Main Authors: Domenica Ronchetti, Vanessa Katia Favasuli, Ilaria Silvestris, Katia Todoerti, Federica Torricelli, Niccolò Bolli, Alessia Ciarrocchi, Elisa Taiana, Antonino Neri
Format: Article
Language:English
Published: Springer 2022-11-01
Series:Discover Oncology
Subjects:
NONO
Multiple myeloma
Therapeutic target
Warburg effect
Online Access:https://doi.org/10.1007/s12672-022-00582-2

Internet

https://doi.org/10.1007/s12672-022-00582-2

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