Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation

Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation

Abstract Background Pluripotent stem cells are attractive progenitor cells for the generation of erythroid cells in vitro as have expansive proliferative potential. However, although embryonic (ESC) and induced pluripotent (iPSC) stem cells can be induced to undergo erythroid differentiation, the ma...

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Bibliographic Details
Main Authors: Kongtana Trakarnsanga, Daniel Ferguson, Deborah E. Daniels, Rebecca E. Griffiths, Marieangela C. Wilson, Kathryn E. Mordue, Abi Gartner, Tatyana N. Andrienko, Annabel Calvert, Alison Condie, Angela McCahill, Joanne C. Mountford, Ashley M. Toye, David J. Anstee, Jan Frayne
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Stem Cell Research & Therapy
Online Access:http://link.springer.com/article/10.1186/s13287-019-1231-z

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http://link.springer.com/article/10.1186/s13287-019-1231-z

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