2-Hydroxy-5-(3,5,7-trihydroxy-4-oxo-4<i>H</i>-chromen-2-yl)phenyl (<i>E</i>)-3-(4-hydroxy-3-methoxyphenyl)acrylate: Synthesis, In Silico Analysis and In Vitro Pharmacological Evaluation

2-Hydroxy-5-(3,5,7-trihydroxy-4-oxo-4<i>H</i>-chromen-2-yl)phenyl (<i>E</i>)-3-(4-hydroxy-3-methoxyphenyl)acrylate: Synthesis, In Silico Analysis and In Vitro Pharmacological Evaluation

Quercetin and ferulic acid are two phytochemicals extensively represented in the plant kingdom and daily consumed in considerable amounts through diets. Due to a common phenolic structure, these two molecules share several pharmacological properties, e.g., antioxidant and free radical scavenging, an...

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Bibliographic Details
Main Authors: Antonella Brizzi, Alfonso Trezza, Ottavia Spiga, Samuele Maramai, Francesco Scorzelli, Simona Saponara, Fabio Fusi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molbank
Subjects:
ferulic acid
quercetin
ester-based derivatives
K<sub>Ca</sub>1.1 channel
Ca<sub>V</sub>1.2 channel
patch-clamp
Online Access:https://www.mdpi.com/1422-8599/2021/3/M1258

Internet

https://www.mdpi.com/1422-8599/2021/3/M1258

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