EGFR and COX-2 Dual Inhibitor: The Design, Synthesis, and Biological Evaluation of Novel Chalcones

EGFR and COX-2 Dual Inhibitor: The Design, Synthesis, and Biological Evaluation of Novel Chalcones

For most researchers, discovering new anticancer drugs to avoid the adverse effects of current ones, to improve therapeutic benefits and to reduce resistance is essential. Because the COX-2 enzyme plays an important role in various types of cancer leading to malignancy enhancement, inhibition of apo...

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Bibliographic Details
Main Authors: Arafa Musa, Ehab M. Mostafa, Syed Nasir Abbas Bukhari, Nasser Hadal Alotaibi, Ahmed H. El-Ghorab, Amr Farouk, AbdElAziz A. Nayl, Mohammed M. Ghoneim, Mohamed A. Abdelgawad
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
EGFR
COX-2
kinase
anticancer
anti-inflammatory
Online Access:https://www.mdpi.com/1420-3049/27/4/1158

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https://www.mdpi.com/1420-3049/27/4/1158

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