Fasting Proinsulin Independently Predicts Incident Type 2 Diabetes in the General Population

Fasting proinsulin levels may serve as a marker of β-cell dysfunction and predict type 2 diabetes (T2D) development. Kidneys have been found to be a major site for the degradation of proinsulin. We aimed to evaluate the predictive value of proinsulin for the risk of incident T2D added to a base mode...

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Bibliographic Details
Main Authors: Sara Sokooti, Wendy A. Dam, Tamas Szili-Torok, Jolein Gloerich, Alain J. van Gool, Adrian Post, Martin H. de Borst, Ron T. Gansevoort, Hiddo J. L. Heerspink, Robin P. F. Dullaart, Stephan J. L. Bakker
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Journal of Personalized Medicine
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Online Access:https://www.mdpi.com/2075-4426/12/7/1131