Insights into Alkaline Phosphatase Anti-Inflammatory Mechanisms

Insights into Alkaline Phosphatase Anti-Inflammatory Mechanisms

Background: The endogenous ecto-enzyme and exogenously administered alkaline phosphatase (ALP) have been evidenced to significantly attenuate inflammatory conditions, including Toll-like receptor 4 (TLR4)-related signaling and cytokine overexpression, barrier tissue dysfunction and oxidative stress,...

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Bibliographic Details
Main Authors: Larissa Balabanova, Georgii Bondarev, Aleksandra Seitkalieva, Oksana Son, Liudmila Tekutyeva
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomedicines
Subjects:
alkaline phosphatase
LPS-induced inflammation
TLR4-NF-kB signaling pathways
immune metabolism
pro-inflammatory metabolism
catabolic phenotype
Online Access:https://www.mdpi.com/2227-9059/12/11/2502

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https://www.mdpi.com/2227-9059/12/11/2502

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