Remote, real-time expert elicitation to determine the prior probability distribution for Bayesian sample size determination in international randomised controlled trials: Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone (BIPED) study

Remote, real-time expert elicitation to determine the prior probability distribution for Bayesian sample size determination in international randomised controlled trials: Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone (BIPED) study

Abstract Background Bayesian methods are increasing in popularity in clinical research. The design of Bayesian clinical trials requires a prior distribution, which can be elicited from experts. In diseases with international differences in management, the elicitation exercise should recruit internat...

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Bibliographic Details
Main Authors: Jingxian Lan, Amy C. Plint, Stuart R. Dalziel, Terry P. Klassen, Martin Offringa, Anna Heath, on behalf of the Pediatric Emergency Research Canada (PERC) KIDSCAN/PREDICT BIPED Study Group
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Trials
Subjects:
Expert elicitation
Bayesian statistics
Randomised controlled trials
Sample size determination
Prior probability distribution
Trial design
Online Access:https://doi.org/10.1186/s13063-022-06240-w

Internet

https://doi.org/10.1186/s13063-022-06240-w

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