SIRT1 Promotes Cisplatin Resistance in Bladder Cancer via Beclin1 Deacetylation-Mediated Autophagy

SIRT1 Promotes Cisplatin Resistance in Bladder Cancer via Beclin1 Deacetylation-Mediated Autophagy

Autophagy-dependent cisplatin resistance poses a challenge in bladder cancer treatment. SIRT1, a protein deacetylase, is involved in autophagy regulation. However, the precise mechanism through which SIRT1 mediates cisplatin resistance in bladder cancer via autophagy remains unclear. In this study,...

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Bibliographic Details
Main Authors: Yan Sun, Xudong Liu, Hang Tong, Hubin Yin, Tinghao Li, Junlong Zhu, Junrui Chen, Linfeng Wu, Xiaoyu Zhang, Xin Gou, Weiyang He
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
bladder cancer
SIRT1
autophagy
deacetylation
cisplatin resistance
Online Access:https://www.mdpi.com/2072-6694/16/1/125

Internet

https://www.mdpi.com/2072-6694/16/1/125

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