Cisplatin Protein Binding Partners and Their Relevance for Platinum Drug Sensitivity

Cisplatin Protein Binding Partners and Their Relevance for Platinum Drug Sensitivity

Cisplatin is a widely used drug in the treatment of various solid tumors, such as ovarian cancer. However, while the acquired resistance significantly limits the success of therapy, some tumors, such as colorectal cancer, are intrinsically insensitive to cisplatin. Only a small amount of intracellul...

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Bibliographic Details
Main Authors: Sophie Möltgen, Eleonora Piumatti, Giuseppe M. Massafra, Sabine Metzger, Ulrich Jaehde, Ganna V. Kalayda
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
cisplatin resistance
BODIPY-cisplatin
oxaliplatin
vimentin
glutathione-S-transferase π
growth factor receptor-bound protein 2
Online Access:https://www.mdpi.com/2073-4409/9/6/1322

Internet

https://www.mdpi.com/2073-4409/9/6/1322

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