Myostatin promotes tenogenic differentiation of C2C12 myoblast cells through Smad3

Myostatin promotes tenogenic differentiation of C2C12 myoblast cells through Smad3

Myostatin, a member of the transforming growth factor‐β (TGF‐β) superfamily, is expressed in developing and adult skeletal muscle and negatively regulates skeletal muscle growth. Recently, myostatin has been found to be expressed in tendons and increases tendon fibroblast proliferation and the expre...

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Bibliographic Details
Main Authors: Kazutaka Uemura, Masanori Hayashi, Toshiro Itsubo, Ayumu Oishi, Hiroko Iwakawa, Masatoshi Komatsu, Shigeharu Uchiyama, Hiroyuki Kato
Format: Article
Language:English
Published: Wiley 2017-04-01
Series:FEBS Open Bio
Subjects:
C2C12
myostatin
Smad3
tenocyte
tenomodulin
Online Access:https://doi.org/10.1002/2211-5463.12200

Internet

https://doi.org/10.1002/2211-5463.12200

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