Distinct plasmablast developmental intermediates produce graded expression of IgM secretory transcripts
Summary: Differentiation into plasma cells (PCs) enables secretion of ∼10,000 immunoglobulin molecules per second. This extraordinary capacity requires the upregulation of PC transcriptional determinants that specify PC fate, increase immunoglobulin mRNA synthesis, coordinate alternative 3′ end proc...
| Main Authors: | , , , , , |
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| Format: | Article |
| Jezik: | English |
| Izdano: |
Elsevier
2025-02-01
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| Serija: | Cell Reports |
| Teme: | |
| Online dostop: | http://www.sciencedirect.com/science/article/pii/S2211124725000543 |