Autophagy-independent effects of autophagy-related-5 (Atg5) on exosome production and metastasis

Autophagy-related-5 (Atg5) and Autophagy-related-16-Like-1 (Atg16L1) canonically participate in autophagy. Recent research demonstrates that apart from this, they also control production of extracellular vesicles called exosomes by regulating acidification of late endosomes. Atg5-mediated exosome pr...

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Bibliographic Details
Main Authors: Huishan Guo, Remy Sadoul, Derrick Gibbings
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2018.1445941