Tryptophan metabolism as bridge between gut microbiota and brain in chronic social defeat stress-induced depression mice

BackgroundsGut microbiota plays a critical role in the onset and development of depression, but the underlying molecular mechanisms are unclear. This study was conducted to explore the relationships between gut microbiota and host’s metabolism in depression.MethodsChronic social defeat stress (CSDS)...

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Bibliographic Details
Main Authors: Jing Xie, Wen-tao Wu, Jian-jun Chen, Qi Zhong, Dandong Wu, Lingchuan Niu, Sanrong Wang, Yan Zeng, Ying Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1121445/full