PERK-mediated antioxidant response is key for pathogen persistence in ticks

PERK-mediated antioxidant response is key for pathogen persistence in ticks

ABSTRACT A crucial phase in the life cycle of tick-borne pathogens is the time spent colonizing and persisting within the arthropod. Tick immunity is emerging as a key force shaping how transmissible pathogens interact with the vector. How pathogens remain in the tick despite immunological pressure...

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Bibliographic Details
Main Authors: Kristin L. Rosche, Joanna Hurtado, Elis A. Fisk, Kaylee A. Vosbigian, Ashley L. Warren, Lindsay C. Sidak-Loftis, Sarah J. Wright, Elisabeth Ramirez-Zepp, Jason M. Park, Dana K. Shaw
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mSphere
Subjects:
Ixodes scapularis
Borrelia burgdorferi
Anaplasma phagocytophilum
tick-borne disease
vector competence
antioxidant response
Online Access:https://journals.asm.org/doi/10.1128/msphere.00321-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00321-23

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