Honokiol Eliminates Glioma/Glioblastoma Stem Cell-Like Cells Via JAK-STAT3 Signaling and Inhibits Tumor Progression by Targeting Epidermal Growth Factor Receptor

Honokiol Eliminates Glioma/Glioblastoma Stem Cell-Like Cells Via JAK-STAT3 Signaling and Inhibits Tumor Progression by Targeting Epidermal Growth Factor Receptor

Malignant gliomas are the most aggressive forms of brain tumors; whose metastasis and recurrence contribute to high rates of morbidity and mortality. Glioma stem cell-like cells are a subpopulation of tumor-initiating cells responsible for glioma tumorigenesis, metastasis, recurrence and resistance...

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Bibliographic Details
Main Authors: Yipu Fan, Weikang Xue, Melitta Schachner, Weijiang Zhao
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cancers
Subjects:
honokiol
glioma/glioblastoma
glioma stem cell
EGFR
apoptosis
metastasis
Online Access:http://www.mdpi.com/2072-6694/11/1/22

Internet

http://www.mdpi.com/2072-6694/11/1/22

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