Refinement of an Established Procedure and Its Application for Identification of Hypoxia in Prostate Cancer Xenografts

Refinement of an Established Procedure and Its Application for Identification of Hypoxia in Prostate Cancer Xenografts

Background: This pre-clinical study was designed to refine a dissection method for validating the use of a 15-gene hypoxia classifier, which was previously established for head and neck squamous cell carcinoma (HNSCC) patients, to identify hypoxia in prostate cancer. Methods: PC3 and DU-145 adenocar...

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Bibliographic Details
Main Authors: Pernille B. Elming, Thomas R. Wittenborn, Morten Busk, Brita S. Sørensen, Mathilde Borg Houlberg Thomsen, Trine Strandgaard, Lars Dyrskjøt, Steffen Nielsen, Michael R. Horsman
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
hypoxia
pre-clinical models
prostate cancer
PC3
DU-145
hypoxia gene signature
Online Access:https://www.mdpi.com/2072-6694/13/11/2602

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https://www.mdpi.com/2072-6694/13/11/2602

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