Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

Abstract Background Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the epigenomic alterations and transcription factors (TFs) which underli...

Full description

Bibliographic Details
Main Authors: Wesley L. Cai, Celeste B. Greer, Jocelyn F. Chen, Anna Arnal-Estapé, Jian Cao, Qin Yan, Don X. Nguyen
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Medical Genomics
Subjects:
ATAC-seq
ChIP-seq
Breast cancer
Metastasis
Transcription factors
Epigenomics
Online Access:http://link.springer.com/article/10.1186/s12920-020-0695-0

Internet

http://link.springer.com/article/10.1186/s12920-020-0695-0

Similar Items