A Comparison of Evans Blue and 4-(<i>p</i>-Iodophenyl)butyryl Albumin Binding Moieties on an Integrin α<sub>v</sub>β<sub>6</sub> Binding Peptide

A Comparison of Evans Blue and 4-(<i>p</i>-Iodophenyl)butyryl Albumin Binding Moieties on an Integrin α<sub>v</sub>β<sub>6</sub> Binding Peptide

Serum albumin binding moieties (ABMs) such as the Evans blue (EB) dye fragment and the 4-(<i>p</i>-iodophenyl)butyryl (IP) have been used to improve the pharmacokinetic profile of many radiopharmaceuticals. The goal of this work was to directly compare these two ABMs when conjugated to a...

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Bibliographic Details
Main Authors: Ryan A. Davis, Sven H. Hausner, Rebecca Harris, Julie L. Sutcliffe
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
albumin binding moieties
peptides
Evans blue
4-(<i>p</i>-iodophenyl)butyric acid
integrin α<sub>v</sub>β<sub>6</sub>
integrin α<sub>v</sub>β<sub>6</sub> binding peptide
Online Access:https://www.mdpi.com/1999-4923/14/4/745

Internet

https://www.mdpi.com/1999-4923/14/4/745

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