Basophils are dispensable for the establishment of protective adaptive immunity against primary and challenge infection with the intestinal helminth parasite Strongyloides ratti.

Infections with helminth parasites are controlled by a concerted action of innate and adaptive effector cells in the frame of a type 2 immune response. Basophils are innate effector cells that may also contribute to the initiation and amplification of adaptive immune responses. Here, we use constitu...

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Bibliographic Details
Main Authors: Martina Reitz, Marie-Luise Brunn, David Voehringer, Minka Breloer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0006992