The Efficacy and Potential Mechanisms of Metformin in the Treatment of COVID-19 in the Diabetics: A Systematic Review

IntroductionDiabetes mellitus (DM) is one of the most common comorbidities among patients with coronavirus disease 2019 (COVID-19) which may exacerbate complications of this new viral infection. Metformin is an anti-hyperglycemic agent with host-directed immune-modulatory effects, which relieve exag...

Full description

Bibliographic Details
Main Authors: Moein Zangiabadian, Seyed Aria Nejadghaderi, Mohammad Mahdi Zahmatkesh, Bahareh Hajikhani, Mehdi Mirsaeidi, Mohammad Javad Nasiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.645194/full