Upregulation of Transferrin Receptor 1 (TfR1) but Not Glucose Transporter 1 (GLUT1) or CD98hc at the Blood–Brain Barrier in Response to Valproic Acid

Upregulation of Transferrin Receptor 1 (TfR1) but Not Glucose Transporter 1 (GLUT1) or CD98hc at the Blood–Brain Barrier in Response to Valproic Acid

Background: Transferrin receptor 1 (TfR1), glucose transporter 1 (GLUT1), and CD98hc are candidates for targeted therapy at the blood–brain barrier (BBB). Our objective was to challenge the expression of TfR1, GLUT1, and CD98hc in brain capillaries using the histone deacetylase inhibitor (HDACi) val...

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Bibliographic Details
Main Authors: Steinunn Sara Helgudóttir, Kasper Bendix Johnsen, Lisa Greve Routhe, Charlotte Laurfelt Munch Rasmussen, Maj Schneider Thomsen, Torben Moos
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Cells
Subjects:
blood–brain barrier
capillary depletion
CD98hc
cell culture
glucose transporter 1
ICP-MS
Online Access:https://www.mdpi.com/2073-4409/13/14/1181

Internet

https://www.mdpi.com/2073-4409/13/14/1181

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