The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design

Abstract Human parainfluenza viruses represent a leading cause of lower respiratory tract disease in children, with currently no available approved drug or vaccine. The viral surface glycoprotein haemagglutinin-neuraminidase (HN) represents an ideal antiviral target. Herein, we describe the first st...

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Bibliographic Details
Main Authors: Larissa Dirr, Ibrahim M. El-Deeb, Leonard M. G. Chavas, Patrice Guillon, Mark von Itzstein
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04656-y