Persistent TLR4 Activation Promotes Hepatocellular Carcinoma Growth through Positive Feedback Regulation by LIN28A/Let-7g miRNA

Persistent TLR4 Activation Promotes Hepatocellular Carcinoma Growth through Positive Feedback Regulation by LIN28A/Let-7g miRNA

Chronic inflammation caused by liver damage or infection plays an important role in the development and progression of hepatocellular carcinoma (HCC). The activation of Toll-like receptors 4 (TLR4) is involved in HCC tumorigenesis. Moreover, high TLR4 expression in HCC has been linked to poor progno...

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Bibliographic Details
Main Authors: I-Ting Chen, An-Chieh Cheng, Yi-Ting Liu, Chieh Yan, Yi-Chen Cheng, Chiung-Fang Chang, Ping-Hui Tseng
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocellular carcinoma
Toll-like receptors 4
LIN28A
let-7g
Online Access:https://www.mdpi.com/1422-0067/23/15/8419

Internet

https://www.mdpi.com/1422-0067/23/15/8419

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