Circular oligomerization is an intrinsic property of synaptotagmin

Circular oligomerization is an intrinsic property of synaptotagmin

Previously, we showed that synaptotagmin1 (Syt1) forms Ca2+-sensitive ring-like oligomers on membranes containing acidic lipids and proposed a potential role in regulating neurotransmitter release (Zanetti et al., 2016). Here, we report that Syt1 assembles into similar ring-like oligomers in solutio...

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Bibliographic Details
Main Authors: Jing Wang, Feng Li, Oscar D Bello, Charles Vaughn Sindelar, Frédéric Pincet, Shyam S Krishnakumar, James E Rothman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
neurotransmitters
membrane fusion
electron microscopy
Online Access:https://elifesciences.org/articles/27441

Internet

https://elifesciences.org/articles/27441

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