High resolution microfluidic single cell transcriptional profiling reveals clinically relevant subtypes among human stem cell populations commonly utilized in cell-based therapies

High resolution microfluidic single cell transcriptional profiling reveals clinically relevant subtypes among human stem cell populations commonly utilized in cell-based therapies

Stem cell therapies can promote neural repair and regeneration, yet controversy regarding optimal cell source and mechanism of action has slowed clinical translation, potentially due to undefined cellular heterogeneity. Single cell resolution is needed to identify clinically relevant subpopulations...

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Bibliographic Details
Main Authors: Robert C. Rennert, Richard eSchäfer, Tonya eBliss, Michael eJanuszyk, Michael eSorkin, Achal S. Achrol, Melanie eRodrigues, Zeshaan N. Maan, Torsten eKluba, Gary K Steinberg, Geoffrey C. Gurtner
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Neurology
Subjects:
Stroke
Neuroregeneration
single cell analysis
Cellular heterogeneity
stem cell therapeutics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00041/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00041/full

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