Leveraging Gene Redundancy to Find New Histone Drivers in Cancer

Histones play a critical role in chromatin function but are susceptible to mutagenesis. In fact, numerous mutations have been observed in several cancer types, and a few of them have been associated with carcinogenesis. Histones are peculiar, as they are encoded by a large number of genes, and the m...

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Bibliographic Details
Main Authors: Daria Ostroverkhova, Daniel Espiritu, Maria J. Aristizabal, Anna R. Panchenko
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/13/3437