Multi-omics analysis reveals the association between elevated KIF18B expression and unfavorable prognosis, immune evasion, and regulatory T cell activation in nasopharyngeal carcinoma

Multi-omics analysis reveals the association between elevated KIF18B expression and unfavorable prognosis, immune evasion, and regulatory T cell activation in nasopharyngeal carcinoma

BackgroundNasopharyngeal carcinoma (NPC) is prevalent in Southern China. The expression profile and functions of kinesin family member 18B (KIF18B) remain unclear in NPC.MethodsBulk and single-cell transcriptome data for NPC were downloaded. KIF18B expression differences in NPC and normal tissues an...

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Bibliographic Details
Main Authors: Siqi Tang, Zhenyu Wu, Lusi Chen, Longjiang She, Weihan Zuo, Weijun Luo, Yang Zhang, Shaoqiang Liang, Guichao Liu, Biyi He, Jinfeng He, Ning Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
KIF18B
nasopharyngeal carcinoma
regulatory T cell
immune infiltration
intercellular communication
epithelial-mesenchymal transition
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1258344/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1258344/full

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