Cross-reactive inhibitory antibody and memory B cell responses to variant strains of Duffy binding protein II at post-Plasmodium vivax infection.

Duffy binding protein region II (DBPII) is considered a strong potential vaccine candidate of blood-stage P. vivax. However, the highly polymorphic nature of this protein often misdirects immune responses, leading them to be strain-specific. Details of cross-reactive humoral immunity to DBPII varian...

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Bibliographic Details
Main Authors: Pongsakorn Thawornpan, Siriruk Changrob, Piyawan Kochayoo, Kittikorn Wangriatisak, Francis B Ntumngia, Sai Lata De, Eun-Taek Han, John H Adams, Patchanee Chootong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0276335