Celastrol ameliorates lupus by promoting apoptosis of autoimmune T cells and preventing autoimmune response in MRL/lpr mice
Objective Celastrol is a bioactive constituent extracted from Tripterygium wilfordii (thunder god vine). It has been demonstrated to have a therapeutic effect on experimental disease models for chronic inflammatory and immune disorders. In the present study, we investigated whether and how celastrol...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2024-03-01
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Series: | Lupus Science and Medicine |
Online Access: | https://lupus.bmj.com/content/11/1/e001057.full |