Celastrol ameliorates lupus by promoting apoptosis of autoimmune T cells and preventing autoimmune response in MRL/lpr mice

Objective Celastrol is a bioactive constituent extracted from Tripterygium wilfordii (thunder god vine). It has been demonstrated to have a therapeutic effect on experimental disease models for chronic inflammatory and immune disorders. In the present study, we investigated whether and how celastrol...

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Bibliographic Details
Main Authors: Ping Li, Xin Liu, Xiang Liu, Hongliang Rui, Tianhong Xie, Huiqiang Liu
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/11/1/e001057.full