O‐GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O‐GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload

O‐GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O‐GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload

Background Protein posttranslational modifications by O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) increase with cardiac hypertrophy, yet the functional effects of these changes are incompletely understood. In other organs, O‐GlcNAc promotes adaptation to acute physiological stressors; however, prolong...

詳細記述

書誌詳細
主要な著者: Wei‐Zhong Zhu, Danny El‐Nachef, Xiulan Yang, Dolena Ledee, Aaron K. Olson
フォーマット: 論文
言語:English
出版事項: Wiley 2019-06-01
シリーズ:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
主題:
cardiac failure
cardiac hypertrophy
O‐GlcNAc
OGT
pressure overload
protein kinase A phosphorylation
オンライン･アクセス:https://www.ahajournals.org/doi/10.1161/JAHA.118.011260

インターネット

https://www.ahajournals.org/doi/10.1161/JAHA.118.011260

類似資料