O‐GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O‐GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload

Background Protein posttranslational modifications by O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) increase with cardiac hypertrophy, yet the functional effects of these changes are incompletely understood. In other organs, O‐GlcNAc promotes adaptation to acute physiological stressors; however, prolong...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Wei‐Zhong Zhu, Danny El‐Nachef, Xiulan Yang, Dolena Ledee, Aaron K. Olson
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Wiley 2019-06-01
Цуврал:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Нөхцлүүд:
Онлайн хандалт:https://www.ahajournals.org/doi/10.1161/JAHA.118.011260