Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice

Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice

Abstract ᅟ Astrocytosis is a reactive process involving cellular, molecular, and functional changes to facilitate neuronal survival, myelin preservation, blood brain barrier function and protective glial scar formation upon brain insult. The overall pro- or anti-inflammatory impact of reactive astro...

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Bibliographic Details
Main Authors: Katrin Pfuhlmann, Sonja C. Schriever, Beata Legutko, Peter Baumann, Luke Harrison, Dhiraj G. Kabra, Emily Violette Baumgart, Matthias H. Tschöp, Cristina Garcia-Caceres, Paul T. Pfluger
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Neuroinflammation
Subjects:
Calcineurin
Ppp3cb
Obesity
Inflammation
Astrocytosis
Microgliosis
Online Access:http://link.springer.com/article/10.1186/s12974-018-1076-x

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http://link.springer.com/article/10.1186/s12974-018-1076-x

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