Direct effects of mast cell proteases, tryptase and chymase, on bronchial epithelial integrity proteins and anti-viral responses

Direct effects of mast cell proteases, tryptase and chymase, on bronchial epithelial integrity proteins and anti-viral responses

Abstract Background Mast cells (MCs) are known to contribute to both acute and chronic inflammation. Bronchial epithelial cells are the first line of defence against pathogens and a deficient anti-viral response has been suggested to play a role in the pathogenesis of asthma exacerbations. However,...

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Bibliographic Details
Main Authors: Sangeetha Ramu, Hamid Akbarshahi, Sofia Mogren, Frida Berlin, Samuel Cerps, Mandy Menzel, Morten Hvidtfeldt, Celeste Porsbjerg, Lena Uller, Cecilia K. Andersson
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Immunology
Subjects:
Asthma
Mast cells
Tryptase
Chymase
Human bronchial epithelial cells
Online Access:https://doi.org/10.1186/s12865-021-00424-w

Internet

https://doi.org/10.1186/s12865-021-00424-w

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