Sulfonated and Carboxymethylated β-Glucan Derivatives with Inhibitory Activity against Herpes and Dengue Viruses

Sulfonated and Carboxymethylated β-Glucan Derivatives with Inhibitory Activity against Herpes and Dengue Viruses

The infection of mammalian cells by enveloped viruses is triggered by the interaction of viral envelope glycoproteins with the glycosaminoglycan, heparan sulfate. By mimicking this carbohydrate, some anionic polysaccharides can block this interaction and inhibit viral entry and infection. As heparan...

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Bibliographic Details
Main Authors: José Louzinho Lopes, Vinicius Seiki Takemura Quinteiro, Jéssica Wouk, Maria Laura Darido, Robert F. H. Dekker, Aneli M. Barbosa-Dekker, Václav Vetvicka, Mário A. A. Cunha, Ligia Carla Faccin-Galhardi, Alexandre Orsato
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
(1→3)(1→6)-β-D-glucan
antivirals
anionic polysaccharides
herpes simplex virus
dengue virus
Online Access:https://www.mdpi.com/1422-0067/22/20/11013

Internet

https://www.mdpi.com/1422-0067/22/20/11013

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