Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation

A simple and efficient protocol has been developed for the direct synthesis of γ-nitrobutyric acid methyl esters under microwave irradiation. This methodology reduces reaction times from days to minutes, compared to conventional conditions. Additionally, these conditions increased yields and provide...

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Bibliographic Details
Main Authors: Francisco D. Díaz-Coutiño, Jaime Escalante
Format: Article
Language:English
Published: MDPI AG 2009-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/14/4/1595/