Animal models of primary biliary cholangitis: status and challenges

Animal models of primary biliary cholangitis: status and challenges

Abstract Background Primary biliary cholangitis (PBC) is an autoimmune liver disease. The aetiology of PBC remains unclear, and its pathogenesis is complex. Animal models are essential to clarify the pathogenesis of PBC and explore the occurrence of early events. Main body Herein, we review recent r...

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Bibliographic Details
Main Authors: Xu Wang, Yi Wei, Yanlei Yang, Yunjiao Yang, Haolong Li, Yongzhe Li, Fengchun Zhang, Li Wang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cell & Bioscience
Subjects:
Primary biliary cholangitis
Genetically modified models
Chemically inducible models
Biologically inducible models
Challenges
Online Access:https://doi.org/10.1186/s13578-023-01170-9

Internet

https://doi.org/10.1186/s13578-023-01170-9

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