Enhancement of saquinavir absorption and accumulation through the formation of solid drug nanoparticles

Abstract Background Nanotechnology is now considered a promising drug delivery method for orally administered hydrophobic drugs to their sites of action. The effect of nanodispersion on cellular transport and accumulation of saquinavir (SQV) was investigated. Methods The transport of five solid drug...

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Bibliographic Details
Main Authors: Gabriel Kigen, Geoffrey Edwards
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40360-018-0275-5